TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic V.V.I.
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant GluN1/GluN2D receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of rat recombinant GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as reduction in current responseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic V.V.I.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2D expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic V.V.I.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2D expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+4nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+5nMAssay Description:Antagonist activity at recombinant rat GluN1a/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic V.V.I.
Curated by ChEMBL
Affinity DataIC50: 4.26E+5nMAssay Description:Negative allosteric modulation of GluN1a/GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glutamate/glyc...More data for this Ligand-Target Pair