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Found 24 of ic50 data for complexid = 50000424,50000454
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.

Curated by ChEMBL
LigandPNGBDBM50498430(CHEMBL3594112)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant GluN1/GluN2D receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509842(CHEMBL4468229)
Affinity DataIC50:  1.30E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531773(CHEMBL4475740)
Affinity DataIC50:  1.40E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509840(CHEMBL4528294)
Affinity DataIC50:  1.70E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509834(CHEMBL4583491)
Affinity DataIC50:  2.20E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509841(CHEMBL4445076)
Affinity DataIC50:  2.70E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531765(CHEMBL4534780)
Affinity DataIC50:  2.90E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531766(CHEMBL4472540)
Affinity DataIC50:  2.90E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509835(CHEMBL4443031)
Affinity DataIC50:  5.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50007024(CHEMBL3237304)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of rat recombinant GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as reduction in current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509838(CHEMBL4440270)
Affinity DataIC50:  5.80E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509844(CHEMBL4528633)
Affinity DataIC50:  8.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531772(CHEMBL4593032)
Affinity DataIC50:  8.60E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509843(CHEMBL4560850)
Affinity DataIC50:  1.00E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.

Curated by ChEMBL
LigandPNGBDBM409486(N-Cyclopropyl-2-[6-[3-(trifluoromethyl)phenyl]pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2D expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.

Curated by ChEMBL
LigandPNGBDBM436689(N-Cyclopropyl-2-[2-oxo-6-[3-(trifluoromethyl)pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2D expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509845(CHEMBL4577751)
Affinity DataIC50:  2.30E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509836(CHEMBL4553292)
Affinity DataIC50:  2.40E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509846(CHEMBL4519099)
Affinity DataIC50:  2.90E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509839(CHEMBL4557334)
Affinity DataIC50:  2.90E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531771(CHEMBL4438845)
Affinity DataIC50:  4.96E+4nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509837(CHEMBL4564143)
Affinity DataIC50: >1.00E+5nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50246910(CHEMBL4084540)
Affinity DataIC50:  1.70E+5nMAssay Description:Antagonist activity at recombinant rat GluN1a/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.

Curated by ChEMBL
LigandPNGBDBM50259886(CHEMBL2333943)
Affinity DataIC50:  4.26E+5nMAssay Description:Negative allosteric modulation of GluN1a/GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glutamate/glyc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed